From the Field

What is HIV and AIDS? Facts, symptoms, and how to help

The HIV and AIDS pandemic has devastated families worldwide, leaving children without the essential care and support they need to survive, grow, and thrive. About 13.8 million children have lost one or both parents to AIDS-related causes.

About 38 million people around the world were living with HIV in 2019, and 1.7 million people contracted the infection that same year.

Every year since 1988, December 1 has been recognized as World AIDS Day to call attention to this scourge that has infected more than 75.7 million people since it was identified in 1981.

“COVID-19 is threatening the progress that the world has made in health and development over the past 20 years, including the gains we have made against HIV,” says Winnie Byanyima, executive director of UNAIDS and under-secretary-general of the United Nations. “Like all epidemics, it is widening the inequalities that already existed.”

Children made vulnerable by AIDS include kids living with HIV, those whose parent or parents have the disease or died from it, and kids in households that take in orphans from families affected by HIV and AIDS.

Challenging the church to care about the AIDS crisis when it was a controversial topic, World Vision spurred global action to support special programs and child sponsorship to help thousands of orphans. Reflecting on the challenges of the late 1990s, World Vision U.S. President Emeritus Rich Stearns remarks, “Everything we do should advance public awareness by making people aware and helping people to care. Sometimes that means challenging the attitudes and beliefs of the culture and proclaiming God’s standards of mercy, justice, and compassion.”

Help care for children and families whose lives have been forever impacted by HIV and AIDS.

FAQs: What you need to know about HIV and AIDS

Explore facts and frequently asked questions about HIV and AIDS, and learn how you can help affected children and families.

Fast facts: HIV and AIDS

  • HIV (human immunodeficiency virus) causes deterioration of the immune system so that the body isn’t able to fend off diseases and infections. AIDS (acquired immune deficiency syndrome) is the most advanced stage of HIV infection.
  • Treatment with combination antiretroviral therapy (ART) keeps the virus from reproducing in the body, so the immune system continues to function.
  • An estimated 38 million people were living with HIV in 2019; 1.8 million of them were children younger than 15.
  • Most children infected with HIV were infected by their mothers during pregnancy, childbirth, or breastfeeding. Elimination of mother-to-child transmission is becoming a reality.
  • About 1.7 million people became infected with HIV during 2019 compared to 2.9 million in 1997.
  • Globally, HIV infection is the greatest risk factor for the development of tuberculosis (TB).

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History of the HIV and AIDS pandemic

Nearly 33 million people have died of AIDS-related illnesses since the start of the epidemic in June 1981. About 13.8 million children under the age of 18 have lost their mother, father, or both parents to AIDS. That number continues to rise.

At the height of the epidemic in 2005, as many as 40.3 million people were living with HIV worldwide, roughly two-thirds of them in Africa. Every day in 2005, more than 13,000 people were newly infected with HIV. About 3.1 million people died of AIDS in 2005, including nearly 600,000 children.

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How can I help children and families affected by HIV and AIDS?

Pray: Ask God that children and families will have the healthcare and nutrition they need to ward off infections and maintain good health.

Give: Support World Vision’s HIV and AIDS care and prevention programs.

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A World Vision HIV/AIDS community counselor, Menes Maruwa, explains how HIV is transmitted to a group of men at a mining camp in Tanzania. Many miners contracted the virus while working away from home at camps like this, then unwittingly infected their wives when they returned to their home communities. (©2001 World Vision/photo by Nigel Marsh)
A World Vision HIV/AIDS community counselor, Menes Maruwa, explains how HIV is transmitted to a group of men at a mining camp in Tanzania. Many miners contracted the virus while working away from home at camps like this, then unwittingly infected their wives when they returned to their home communities. (©2001 World Vision/photo by Nigel Marsh)

What is the difference between HIV and AIDS?

HIV (human immunodeficiency virus) causes deterioration of the immune system (immune deficiency), so the body isn’t able to fend off diseases and infections. While there is no cure for HIV infection, there are drugs that can control the virus and help prevent transmission.

AIDS (acquired immune deficiency syndrome) is the term applied to the most advanced stages of HIV infection. AIDS is defined by the development of any of more than 20 opportunistic infections or HIV-related cancers.

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How is HIV spread?

HIV is transmitted by certain body fluids through unprotected sexual intercourse, transfusions of contaminated blood, use of contaminated surgical equipment, syringes, or tattooing equipment. Mothers can also transmit the disease to children during pregnancy, childbirth, or through breast milk.

Education and testing are important to prevent the spread of HIV. When women are tested early in their pregnancy, any found HIV-positive can start treatment to prevent the spread of the infection to their child.

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What are the symptoms of HIV and AIDS?

Within two weeks of exposure to HIV, some people develop flu-like symptoms such as chills, fever, sore throat, night sweats, rash, fatigue, mouth ulcers, or swollen lymph nodes. Not everyone shows any or all of the symptoms and the virus may not yet be detectable in a test for a few weeks.

An untreated HIV infection will eventually wear down the immune system and become full-blown AIDS, with much more severe symptoms. They include rapid weight loss, extreme tiredness, recurring fever, swelling of the lymph glands, long bouts of diarrhea, blotchy skin, mouth sores, and memory loss.

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What is the treatment for HIV and AIDS? Is there a cure?

There is no cure for HIV. However, antiretroviral drugs offer very effective treatment. They fight HIV by stopping or interfering with the reproduction of the virus in the body, reducing the amount of virus in the body. In people who adhere to treatment with antiretroviral drugs, the progression of the disease can be slowed way down. They can remain well and productive for a long time, even in low-income countries.

When HIV becomes AIDS, with its severe symptoms, it’s much more difficult to treat because the other infections or cancers involved require other forms of treatment. Tuberculosis is the most common cause of death in patients with AIDS, so new treatment regimens are being sought for TB and other diseases that piggyback on AIDS.

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How many people living with HIV are accessing antiretroviral therapy?

As of June 2020, 26 million people — a little more than 68% of people with HIV — were accessing antiretroviral therapy, according to UNAIDS. That’s an increase from 6.4 million in 2009. In 2019, 85% of pregnant women living with HIV had access to antiretroviral medicines to prevent transmission of HIV to their child.

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Prenatal HIV testing_Cambodia
A pregnant woman receives voluntary confidential counseling and HIV testing at a World Vision clinic in Cambodia. (©2010 World Vision/photo by Sopheak Kong)

What impact is COVID-19 expected to have on treating HIV?

The coronavirus pandemic could affect low- and middle-income countries’ ability to access medicine used to treat HIV, according to UNAIDS. There’s concern that closures and disruptions will impact the production of antiretroviral medicines and drive costs up.

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What is the progress against HIV and AIDS?

UNAIDS detailed in its 2016 report the results of its six-year global plan to eliminate new HIV infections among children and keep their mothers alive.

More than 90% of children who contracted HIV received it from their infected mother while in the womb, during birth, or while breastfeeding. The 21 targeted countries accounted for the vast majority of people living with AIDS globally, according to the joint U.N. program.

In six years, those countries helped 1.2 million children avoid HIV infection. More than 2 million more pregnant women started receiving life-saving antiretroviral therapy, which can hold the virus at bay and prevent them from developing AIDS. Contracting HIV no longer is a death sentence because treatment is more effective and readily available to many. Among the greatest gains were in Uganda, where public health workers and families reduced new HIV infections among children by 86%. South Africa and Burundi both reduced infection rates by 84%.

Seven countries reduced HIV infections among children by more than 70% between 2009 and 2016:

  • Uganda — 86%
  • Burundi — 84%
  • South Africa — 84%
  • Eswatini (Swaziland) — 80%
  • Namibia — 79%
  • Mozambique — 75%
  • Malawi — 71%

The 14 other countries reduced new HIV cases among children by anywhere from 21% to 69%.

Of the countries on the list, World Vision works to reduce mother-to-child transmission of HIV in Ghana, South Africa, Malawi, Zambia, and Ethiopia

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Can HIV and AIDS be eradicated?

Researchers are a long way from eliminating the virus, but ever closer to stopping the spread of HIV and AIDS. As scientists have studied HIV and found ways to fight it with antiretroviral drugs, they also discovered that the virus can hide within long-lived immune cells throughout the body. To eradicate the virus within an individual would mean attacking the virus in all the cellular reservoirs where it hides.

But what about eradicating the spread of the disease? That’s another matter, and that’s much more doable. There are ways to prevent new infections and to keep people living with HIV healthy. Antiretroviral treatments not only save the lives of people with HIV, but they can also reduce the chance of infected people spreading the disease.

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Is there an HIV vaccine?

No, though not for lack of trying. There have been at least 40 potential HIV vaccines in human trials, and other trials are being developed.

A major obstacle to developing an HIV vaccine is that it would need to stimulate an immune response, while the immune system — especially the lymph glands — are the target of the infection, too.

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How are women and girls affected by HIV?

HIV and AIDS remain the leading cause of death among women ages 15 to 49. Young women are the left-behind population when it comes to HIV prevention, care, and treatment, according to UNAIDS.

Globally, women and girls accounted for about 48% of all new HIV infections in 2019. Every week, about 5,500 young women ages 15 to 24 years become infected with HIV.

In sub-Saharan Africa, women and girls accounted for 59% of all new HIV infections. Young women there are more than twice as likely to acquire HIV as their male peers. Lack of knowledge on how to protect themselves from HIV, gender inequalities including gender-based violence, and stigma are barriers that impact access to available HIV prevention, care, and treatment services for adolescent girls and young women.

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How are children most likely to contract HIV?

The majority of children with HIV contracted it from their infected mother while in the womb, during birth, or while breastfeeding. That’s why World Vision’s efforts focus on helping pregnant women with HIV understand their situation and get the treatment they need. It not only helps them rejuvenate their health, but it protects their babies from contracting the disease.

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World Vision U.S. President Rich Stearns prays with HIV-positive widow Agnes Lowiji and her five children. World Vision is working to reduce the stigma of HIV in her community and helping her to care for her children. (©2004 World Vision/ photo by Jon Warren)
World Vision U.S. President Rich Stearns prays with HIV-positive widow Agnes Lowiji and her five children. World Vision is working to reduce the stigma of HIV in her community and helping her to care for her children. (©2004 World Vision/photo by Jon Warren)

How’s World Vision responding to the HIV and AIDS pandemic?

As AIDS devastated rural communities where we were working, World Vision called upon churches to join its HIV and AIDS Hope Initiative to help thousands of orphans and vulnerable children.

HIV and AIDS Hope Initiative

August 1998: World Vision U.S. President Emeritus Rich Stearns visits Uganda, meets AIDS orphans, and learns about the impact of AIDS on children.

July 2000: Wilfred Mlay, World Vision’s Africa region vice president, appeals for help to fight AIDS in Africa.

December 1, 2000: On World AIDS Day, World Vision International President Dean Hirsch announces the formation of a global initiative to fight against HIV and AIDS.

January 12, 2002: The Hope Initiative officially launches at a conference in South Africa attended by staff from the 17 African countries hardest hit by HIV and AIDS.

Three key components of the work are prevention, care, and advocacy:

  1. Prevent new cases, focusing on children, high-risk groups, and pregnant and lactating mothers
  2. Improve the quality of care for children affected by AIDS, including orphans and those living with HIV-positive parents
  3. Advocate for public policies and programs to stem the spread of HIV and provide care for people living with or affected by HIV and AIDS

2003: World Vision receives its first grant for HIV programming. We introduce the Channels of Hope curriculum in Africa to engage faith leaders and congregations in advocacy and prevention against HIV and AIDS.

2005: World Vision scales up HIV programming outside of Africa.

World Vision Myanmar's Community Development Facilitator Saing Zaw Hmun hands out literature about the risks of HIV/AIDS to bus and truck drivers, ticket sellers, route operators and market traders at a Mandalay bus station. Because of their risky behavior, the virus spreads throughout the country along the road network.
A World Vision community development facilitator in Myanmar, Saing Zaw Hmun, hands out literature about the risks of HIV and AIDS to bus and truck drivers, ticket sellers, route operators, and market traders at a Mandalay bus station. By having unprotected sex with travelers, they could spread the virus throughout the country along the road network. (©2004 World Vision/photo by James East)

2006: World Vision introduces Channels of Hope in Latin America, the Caribbean, the Middle East, Eastern Europe, and the Asia Pacific regions.

2009: A Channels of Hope study in three countries affirms the importance of addressing stigma through faith communities and mobilizing community action.

December 1, 2010: On World AIDS Day, World Vision phases out the Hope Initiative now that HIV and AIDS programming is mainstreamed in World Vision’s program areas.

Beyond the Hope Initiative: We dare not stop

World Vision’s made much progress in mitigating the impact of HIV on children, as well as women and men. Thanks to the support of the international public health community and the generosity of the American people through USAID’s President’s Emergency Plan For AIDS Relief (PEPFAR), the number of people on lifelong, life-saving antiretroviral therapy has greatly increased. Through PEPFAR, the number of children accessing antiretroviral treatment has more than doubled since 2014 and is now at 1 million annually.

Through World Vision’s Channels of Hope program, clergy and lay leaders from various faith communities learn about critical issues like gender violence, child protection, and HIV and AIDS. Together, they implement solutions that demonstrate love and caring.

About 220,000 World Vision–trained community health workers throughout Africa play an ongoing role as they work with patients and community leaders to help HIV- and AIDS-affected families.

WVUS staff and donors distribute medical kits to caregivers in Lesotho. Seventeen churches in the areas have teams of caregivers. Each member is expected to take care of at least three chronically ill patients using their donated caregiver kit. (©2008 World Vision/photo by Makopano Setsatsi)
World Vision staff and donors distribute medical kits to caregivers in Lesotho. Seventeen churches in the area have teams of caregivers. Each member is expected to take care of at least three chronically ill patients using their donated caregiver kit. (©2008 World Vision/photo by Makopano Setsatsi)

Efforts focus on helping pregnant women with HIV understand their health status and get the treatment they need. It not only helps them recover their health, but it protects their babies from contracting the disease.

World Vision partners with governments to influence healthcare policy and with schools to promote HIV and AIDS awareness. Other partnerships assist community care providers in maintaining relationships and monitoring care. Also, church leaders can help reduce stigma and lead a community response to support people suffering from the disease. While these countries have made monumental progress, the work continues.

In 2017, World Vision carried out HIV and AIDS work under the Global Fund in the Democratic Republic of the Congo, Haiti, Kenya, Malawi, and Zimbabwe that benefited more than 845,000 people with programs that:

  • Provide HIV testing
  • Prevent HIV in adolescent girls and young women
  • Screen HIV-positive people for tuberculosis and start them on TB prevention
  • Enroll HIV-positive people in antiretroviral drug programs
  • Train young people in life skills to prevent risky behavior
  • Improve service delivery to HIV-affected populations
  • Support HIV service providers
  • Organize community groups for HIV prevention and care

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Chris Huber and Sevil Omer of World Vision’s staff in the U.S. contributed to this article.

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